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Initial: 6.25-12.5 mg PO q8hr in conjunction with cardiac glycoside and diuretic therapy. Target therapy: 50 mg q8hr. 450 mg/day maximum. Left Ventricular Dysfunction After Myocardial Infarction. 6.25 mg PO initially followed by 12.5 mg q8hr. Increase to 25 mg PO q8hr over next few days; THEN. Target dose: 50 mg PO q8hr. Diabetic Nephropathy ... alpentin 100 mg